Derek isn’t the only major return of ‘Grey’s Anatomy’ season 17. There’s (at least) one other person on the beach. HL is investigating theories about the past cast members most likely to return.

Take a look back at some of the most dramatic on-set moments from ‘Grey’s Anatomy.’ From Isaiah Washington and Katherine Heigl’s exits, to Ellen Pompeo’s salary negotiations, and more!

After Patrick Dempsey’s surprise return to ‘Grey’s Anatomy,’ the actor and co-star, Ellen Pompeo, opened up about how (and WHY) their on-screen reunion came about.

‘Grey’s Anatomy’ returns for season 17 on Nov. 12 with the doctors facing one of their biggest challenges yet: the COVID-19 pandemic. HollywoodLife has the answers to all your questions about the cast, storylines, and more.

Ellen Pompeo admitted why she ‘made choices’ to stay on ‘Grey’s Anatomy’ for the long term and explained how the show, which she considers ‘a blessing’, has affected her family life, in a new podcast interview.

Sandra Oh revealed that she sometimes battled with ‘Grey’s Anatomy’ writers about Cristina Yang’s storylines, even going ‘toe-to-toe’ with creator Shonda Rimes when necessary.

After over 10 years of marriage and three children together, ‘Grey’s Anatomy’ actress Caterina Scorscone and her husband, Rob Giles, have decided to go their separate ways and begin divorce proceedings.

Ellen Pompeo talked all things Grey’s Anatomy in a new Instagram Live, revealing her thoughts on the first six seasons of the show, and its original cast.

Finding out what’s wrong with Richard was everyone’s main concern during the April 2 episode of ‘Grey’s Anatomy.’ Meredith teamed up with one character in particular to figure out Richard’s diagnosis.

DeLuca’s behavior became more alarming during the March 20 episode of ‘Grey’s Anatomy’ and he was suspended by the end of the episode. Plus, Amelia told Teddy and Owen about the results of the paternity test.